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TRPswitch — a step function chemo-optogenetic ligand for the vertebrate TRPA1 channel

Chemo-optogenetics has produced powerful tools for optical control of cell activity, but current tools suffer from a variety of limitations including low unitary conductance, the need to modify the target channel, or the inability to control both on and off switching. Using a zebrafish behavior-base...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lam, Pui-Ying, Thawani, Aditya R., Balderas, Enrique, White, Andrew J.P., Chaudhuri, Dipayan, Fuchter, Matthew J., Peterson, Randall T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8011302/
https://ncbi.nlm.nih.gov/pubmed/32966062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c06811
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