Cartilaginous fish class II genes reveal unprecedented old allelic lineages and confirm the late evolutionary emergence of DM

Cartilaginous fish (chimaeras, rays and sharks) are the most basal extant jawed vertebrates with an adaptive immune system based on the Major Histocompatibility Complex (MHC). Despite being a key taxon in the evolution of vertebrate adaptive immunity, no comprehensive characterization of MHC class I...

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Veröffentlicht in:Mol Immunol
Hauptverfasser: Almeida, Tereza, Gaigher, Arnaud, Muñoz-Mérida, Antonio, Neves, Fabiana, Castro, L. Filipe C., Flajnik, Martin F., Ohta, Yuko, Esteves, Pedro J., Veríssimo, Ana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010645/
https://ncbi.nlm.nih.gov/pubmed/33126081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2020.10.003
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