Subunit Vaccines Using TLR Triagonist Combination Adjuvants Provide Protection Against Coxiella burnetii While Minimizing Reactogenic Responses

Q fever is caused by the obligate intracellular bacterium, Coxiella burnetii, a designated potential agent of bioterrorism because of its route of transmission, resistance to disinfectants, and low infectious dose. The only vaccine licensed for human use is Q-VAX(®) (Seqirus, licensed in Australia),...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Fratzke, Alycia P., Jan, Sharon, Felgner, Jiin, Liang, Li, Nakajima, Rie, Jasinskas, Algis, Manna, Saikat, Nihesh, Fnu N., Maiti, Sampa, Albin, Tyler J., Esser-Kahn, Aaron P., Davies, D. Huw, Samuel, James E., Felgner, Philip L., Gregory, Anthony E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010241/
https://ncbi.nlm.nih.gov/pubmed/33815413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.653092
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