β-Hexosaminidases Along the Secretory Pathway of Nicotiana benthamiana Have Distinct Specificities Toward Engineered Helminth N-Glycans on Recombinant Glycoproteins

Secretions of parasitic worms (helminths) contain a wide collection of immunomodulatory glycoproteins with the potential to treat inflammatory disorders, like autoimmune diseases. Yet, the identification of single molecules that can be developed into novel biopharmaceuticals is hampered by the limit...

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Detalhes bibliográficos
Publicado no:Front Plant Sci
Main Authors: Alvisi, Nicolò, van Noort, Kim, Dwiani, Sarlita, Geschiere, Nathan, Sukarta, Octavina, Varossieau, Koen, Nguyen, Dieu-Linh, Strasser, Richard, Hokke, Cornelis H., Schots, Arjen, Wilbers, Ruud H. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Plant Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010188/
https://ncbi.nlm.nih.gov/pubmed/33815445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2021.638454
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