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Meteorin-Like Ameliorates β Cell Function by Inhibiting β Cell Apoptosis of and Promoting β Cell Proliferation via Activating the WNT/β-Catenin Pathway

Meteorin-like (Metrnl) is a newly discovered myokine. Plasma Metrnl is decreased in subjects with newly diagnosed type 2 diabetes (T2D) and correlated with insulin resistance. This study aims to determine the effects of Metrnl on the apoptosis and proliferation of β cell. Mouse insulinoma MIN6 cells...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Hu, Wenchao, Wang, Rui, Sun, Bei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010136/
https://ncbi.nlm.nih.gov/pubmed/33815109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.627147
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