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Dengue Virus Envelope Protein Domain III Induces Nlrp3 Inflammasome-Dependent NETosis-Mediated Inflammation in Mice

Abnormal immune responses and cytokine storm are involved in the development of severe dengue, a life-threatening disease with high mortality. Dengue virus-induced neutrophil NETosis response is associated with cytokine storm; while the role of viral factors on the elicitation of excessive inflammat...

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Pubblicato in:Front Immunol
Autori principali: Lien, Te-Sheng, Sun, Der-Shan, Hung, Shih-Che, Wu, Wen-Sheng, Chang, Hsin-Hou
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009969/
https://ncbi.nlm.nih.gov/pubmed/33815373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.618577
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