ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors

[Image: see text] Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible for colistin resistance mediated by lipid A aminoarabinosyl...

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Bibliografski detalji
Izdano u:J Org Chem
Glavni autori: Quaglio, Deborah, Mangoni, Maria Luisa, Stefanelli, Roberta, Corradi, Silvia, Casciaro, Bruno, Vergine, Valeria, Lucantoni, Federica, Cavinato, Luca, Cammarone, Silvia, Loffredo, Maria Rosa, Cappiello, Floriana, Calcaterra, Andrea, Erazo, Silvia, Ghirga, Francesca, Mori, Mattia, Imperi, Francesco, Ascenzioni, Fiorentina, Botta, Bruno
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009527/
https://ncbi.nlm.nih.gov/pubmed/32806095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c01459
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