ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors

[Image: see text] Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible for colistin resistance mediated by lipid A aminoarabinosyl...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Quaglio, Deborah, Mangoni, Maria Luisa, Stefanelli, Roberta, Corradi, Silvia, Casciaro, Bruno, Vergine, Valeria, Lucantoni, Federica, Cavinato, Luca, Cammarone, Silvia, Loffredo, Maria Rosa, Cappiello, Floriana, Calcaterra, Andrea, Erazo, Silvia, Ghirga, Francesca, Mori, Mattia, Imperi, Francesco, Ascenzioni, Fiorentina, Botta, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009527/
https://ncbi.nlm.nih.gov/pubmed/32806095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c01459
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