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Simple Model of Protein Energetics To Identify Ab Initio Folding Transitions from All-Atom MD Simulations of Proteins

[Image: see text] A fundamental requirement to predict the native conformation, address questions of sequence design and optimization, and gain insights into the folding mechanisms of proteins lies in the definition of an unbiased reaction coordinate that reports on the folding state without the nee...

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Détails bibliographiques
Publié dans:J Chem Theory Comput
Auteurs principaux: Meli, Massimiliano, Morra, Giulia, Colombo, Giorgio
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2020
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009504/
https://ncbi.nlm.nih.gov/pubmed/32693598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.0c00524
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