Aerobic glycolysis supports hepatitis B virus protein synthesis through interaction between viral surface antigen and pyruvate kinase isoform M2

As an intracellular pathogen, the reproduction of the hepatitis B virus (HBV) depends on the occupancy of host metabolism machinery. Here we test a hypothesis if HBV may govern intracellular biosynthesis to achieve a productive reproduction. To test this hypothesis, we set up an affinity purificatio...

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Udgivet i:PLoS Pathog
Main Authors: Wu, Yi-Hsuan, Yang, Yi, Chen, Ching-Hung, Hsiao, Chia-Jen, Li, Tian-Neng, Liao, Kuan-Ju, Watashi, Koichi, Chen, Bor-Sen, Wang, Lily Hui-Ching
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009439/
https://ncbi.nlm.nih.gov/pubmed/33720996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008866
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