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Decreased Levels of Blood AMPKα1 but not AMPKα2 Isoform in Patients with Mild Cognitive Impairment and Alzheimer’s Disease: A Pilot Study
BACKGROUND: There is an urgent need to develop feasible biomarkers for diagnosis and prognosis of Alzheimer’s disease (AD). Mounting evidence implicates that dysregulation of energy metabolism is a key and early event in AD pathogenesis. AMP-activated protein kinase (AMPK) is a central molecular sen...
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| Publicado no: | J Alzheimers Dis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8009325/ https://ncbi.nlm.nih.gov/pubmed/32444538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-191189 |
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