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Recent advances in understanding hereditary spastic paraplegias and emerging therapies

Hereditary spastic paraplegias (HSPs) are a group of rare, inherited, neurological diseases characterized by broad clinical and genetic heterogeneity. Lower-limb spasticity with first motoneuron involvement is the core symptom of all HSPs. As spasticity is a syndrome and not a disease, it develops o...

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Detalhes bibliográficos
Publicado no:Fac Rev
Main Authors: Lallemant-Dudek, Pauline, Darios, Frederic, Durr, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Faculty Opinions Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009193/
https://ncbi.nlm.nih.gov/pubmed/33817696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/r/10-27
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