nNOS regulates ciliated cell polarity, ciliary beat frequency, and directional flow in mouse trachea

Clearance of the airway is dependent on directional mucus flow across the mucociliary epithelium, and deficient flow is implicated in a range of human disorders. Efficient flow relies on proper polarization of the multiciliated cells and sufficient ciliary beat frequency. We show that NO, produced b...

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Veröffentlicht in:Life Sci Alliance
Hauptverfasser: Mikhailik, Anatoly, Michurina, Tatyana V, Dikranian, Krikor, Hearn, Stephen, Maxakov, Vladimir I, Siller, Saul S, Takemaru, Ken-Ichi, Enikolopov, Grigori, Peunova, Natalia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Life Science Alliance LLC 2021
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008965/
https://ncbi.nlm.nih.gov/pubmed/33653689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000981
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