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Efficient and flexible simulation-based sample size determination for clinical trials with multiple design parameters
Simulation offers a simple and flexible way to estimate the power of a clinical trial when analytic formulae are not available. The computational burden of using simulation has, however, restricted its application to only the simplest of sample size determination problems, often minimising a single...
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| Udgivet i: | Stat Methods Med Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publications
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8008419/ https://ncbi.nlm.nih.gov/pubmed/33267735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280220975790 |
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