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Embedding a COVID-19 group sequential clinical trial within an ongoing trial: lessons from an unusual experience

The Cape-Covid trial is an embedded clinical trial within the ongoing Cape-Cod trial. The Covid-19 pandemic appeared while we were conducting a randomized trial assessing the effectiveness of corticosteroids in severe community-acquired pneumonia. We took advantage of this ongoing trial to embed a s...

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Dettagli Bibliografici
Pubblicato in:Stat Biopharm Res
Autori principali: Dequin, Pierre-François, Gouge, Amélie Le, Tavernier, Elsa, Giraudeau, Bruno, Zohar, Sarah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008347/
https://ncbi.nlm.nih.gov/pubmed/34191980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2020.1800509
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