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Connective tissue growth factor promotes retinal pigment epithelium mesenchymal transition via the PI3K/AKT signaling pathway

Proliferative vitreoretinopathy (PVR) is a disease leading to the formation of contractile preretinal membranes (PRMs) and is one of the leading causes of blindness. Connective tissue growth factor (CTGF) has been identified as a possible key determinant of progressive tissue fibrosis and excessive...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Wang, Yafen, Chang, Tianfang, Wu, Tong, Ye, Wei, Wang, Yusheng, Dou, Guorui, Du, Hongjun, Hui, Yannian, Guo, Changmei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008218/
https://ncbi.nlm.nih.gov/pubmed/33760200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12028
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