Metabolic Reprogramming and Inflammatory Response Induced by D-Lactate in Bovine Fibroblast-Like Synoviocytes Depends on HIF-1 Activity

Acute ruminal acidosis (ARA) occurs after an excessive intake of rapidly fermentable carbohydrates and is characterized by the overproduction of D-lactate in the rumen that reaches the bloodstream. Lameness presentation, one of the primary consequences of ARA in cattle, is associated with the occurr...

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Detalhes bibliográficos
Publicado no:Front Vet Sci
Main Authors: Quiroga, John, Alarcón, Pablo, Manosalva, Carolina, Teuber, Stefanie, Taubert, Anja, Hermosilla, Carlos, Hidalgo, María Angélica, Carretta, María Daniella, Burgos, Rafael Agustín
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Veterinary Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007789/
https://ncbi.nlm.nih.gov/pubmed/33796579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2021.625347
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