A prostate-specific membrane antigen (PSMA)-targeted prodrug with a favorable in vivo toxicity profile

Prostate-specific membrane antigen (PSMA) is a promising target for the treatment of advanced prostate cancer (PC) and various solid tumors. Although PSMA-targeted radiopharmaceutical therapy (RPT) has enabled significant imaging and prostate-specific antigen (PSA) responses, accumulating clinical d...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Boinapally, Srikanth, Ahn, Hye-Hyun, Cheng, Bei, Brummet, Mary, Nam, Hwanhee, Gabrielson, Kathleen L., Banerjee, Sangeeta R., Minn, Il, Pomper, Martin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007718/
https://ncbi.nlm.nih.gov/pubmed/33782486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-86551-1
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