Bromodomain protein BRD4 is an epigenetic activator of B7-H6 expression in acute myeloid leukemia

B7-H6, a ligand for the NK activating receptor NKp30, has been identified as a biomarker of poor prognosis in several solid cancers. However, little is known about the role of B7-H6 and the mechanisms that control its expression in acute myeloid leukemia (AML). Epigenome modulation, including epigen...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Baragaño Raneros, Aroa, Rodriguez, Ramon M, Bernardo Flórez, Aida, Palomo, Pilar, Colado, Enrique, Minguela, Alfredo, Suárez Álvarez, Beatriz, López-Larrea, Carlos
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007156/
https://ncbi.nlm.nih.gov/pubmed/33796404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1897294
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