SARS-CoV-2 viral dynamics in non-human primates

Non-human primates infected with SARS-CoV-2 exhibit mild clinical signs. Here we used a mathematical model to characterize in detail the viral dynamics in 31 cynomolgus macaques for which nasopharyngeal and tracheal viral load were frequently assessed. We identified that infected cells had a large b...

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Publicado en:PLoS Comput Biol
Main Authors: Gonçalves, Antonio, Maisonnasse, Pauline, Donati, Flora, Albert, Mélanie, Behillil, Sylvie, Contreras, Vanessa, Naninck, Thibaut, Marlin, Romain, Solas, Caroline, Pizzorno, Andres, Lemaitre, Julien, Kahlaoui, Nidhal, Terrier, Olivier, Ho Tsong Fang, Raphael, Enouf, Vincent, Dereuddre-Bosquet, Nathalie, Brisebarre, Angela, Touret, Franck, Chapon, Catherine, Hoen, Bruno, Lina, Bruno, Rosa Calatrava, Manuel, de Lamballerie, Xavier, Mentré, France, Le Grand, Roger, van der Werf, Sylvie, Guedj, Jérémie
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007039/
https://ncbi.nlm.nih.gov/pubmed/33730053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008785
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