CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression

CD44 is a transmembrane glycoprotein, the phosphorylation of which can directly trigger intracellular signaling, particularly Akt protein, for supporting cell growth, motility and invasion. This study examined the role of CD44 on the progression of Cholangiocarcinoma (CCA) using metabolic profiling...

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Опубликовано в: :PLoS One
Главные авторы: Thanee, Malinee, Dokduang, Hasaya, Kittirat, Yingpinyapat, Phetcharaburanin, Jutarop, Klanrit, Poramate, Titapun, Attapol, Namwat, Nisana, Khuntikeo, Narong, Wangwiwatsin, Arporn, Saya, Hideyuki, Loilome, Watcharin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2021
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007026/
https://ncbi.nlm.nih.gov/pubmed/33780455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245871
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