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CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression
CD44 is a transmembrane glycoprotein, the phosphorylation of which can directly trigger intracellular signaling, particularly Akt protein, for supporting cell growth, motility and invasion. This study examined the role of CD44 on the progression of Cholangiocarcinoma (CCA) using metabolic profiling...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8007026/ https://ncbi.nlm.nih.gov/pubmed/33780455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245871 |
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