CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression

CD44 is a transmembrane glycoprotein, the phosphorylation of which can directly trigger intracellular signaling, particularly Akt protein, for supporting cell growth, motility and invasion. This study examined the role of CD44 on the progression of Cholangiocarcinoma (CCA) using metabolic profiling...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Thanee, Malinee, Dokduang, Hasaya, Kittirat, Yingpinyapat, Phetcharaburanin, Jutarop, Klanrit, Poramate, Titapun, Attapol, Namwat, Nisana, Khuntikeo, Narong, Wangwiwatsin, Arporn, Saya, Hideyuki, Loilome, Watcharin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007026/
https://ncbi.nlm.nih.gov/pubmed/33780455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245871
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