CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression

CD44 is a transmembrane glycoprotein, the phosphorylation of which can directly trigger intracellular signaling, particularly Akt protein, for supporting cell growth, motility and invasion. This study examined the role of CD44 on the progression of Cholangiocarcinoma (CCA) using metabolic profiling...

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Vydáno v:PLoS One
Hlavní autoři: Thanee, Malinee, Dokduang, Hasaya, Kittirat, Yingpinyapat, Phetcharaburanin, Jutarop, Klanrit, Poramate, Titapun, Attapol, Namwat, Nisana, Khuntikeo, Narong, Wangwiwatsin, Arporn, Saya, Hideyuki, Loilome, Watcharin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007026/
https://ncbi.nlm.nih.gov/pubmed/33780455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245871
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