CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression

CD44 is a transmembrane glycoprotein, the phosphorylation of which can directly trigger intracellular signaling, particularly Akt protein, for supporting cell growth, motility and invasion. This study examined the role of CD44 on the progression of Cholangiocarcinoma (CCA) using metabolic profiling...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Thanee, Malinee, Dokduang, Hasaya, Kittirat, Yingpinyapat, Phetcharaburanin, Jutarop, Klanrit, Poramate, Titapun, Attapol, Namwat, Nisana, Khuntikeo, Narong, Wangwiwatsin, Arporn, Saya, Hideyuki, Loilome, Watcharin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2021
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8007026/
https://ncbi.nlm.nih.gov/pubmed/33780455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245871
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