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A heterochromatin inducing protein differentially recognizes self versus foreign genomes
Krüppel-associated box-domain zinc finger protein (KRAB-ZFP) transcriptional repressors recruit TRIM28/KAP1 to heterochromatinize the mammalian genome while also guarding the host by silencing invading foreign genomes. However, how a KRAB-ZFP recognizes target sequences in the natural context of its...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8007004/ https://ncbi.nlm.nih.gov/pubmed/33730092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009447 |
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