Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment

INTRODUCTION: Current views of human evolution, as supported by the fossil record, indicate that many hominin lineage branches arose, but only one survived to the present. Neanderthals and Denisovans, two of these extinct lineages, are our closest evolutionary relatives and therefore provide the mos...

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Pubblicato in:Science
Autori principali: Trujillo, Cleber A., Rice, Edward S., Schaefer, Nathan K., Chaim, Isaac A., Wheeler, Emily C., Madrigal, Assael A., Buchanan, Justin, Preissl, Sebastian, Wang, Allen, Negraes, Priscilla D., Szeto, Ryan A., Herai, Roberto H., Huseynov, Alik, Ferraz, Mariana S. A., Borges, Fernando S., Kihara, Alexandre H., Byrne, Ashley, Marin, Maximillian, Vollmers, Christopher, Brooks, Angela N., Lautz, Jonathan D., Semendeferi, Katerina, Shapiro, Beth, Yeo, Gene W., Smith, Stephen E. P., Green, Richard E., Muotri, Alysson R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006534/
https://ncbi.nlm.nih.gov/pubmed/33574182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax2537
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