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Reduced Vitellogenesis and Female Fertility in Gper Knockout Zebrafish

The role G-protein coupled estrogen receptor (GPER) plays in vertebrate reproduction remains controversial. To investigate GPER’s reproductive role, we generated a gper zebrafish mutant line (gper(−/−)) using TALENs. Gper mutant females exhibited reduced fertility with a 40.85% decrease in embryo pr...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Wu, Xin-Jun, Williams, Marcus Jermaul, Kew, Kimberly Ann, Converse, Aubrey, Thomas, Peter, Zhu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006473/
https://ncbi.nlm.nih.gov/pubmed/33790865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2021.637691
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