A Meta-Analysis of Brain DNA Methylation Across Sex, Age, and Alzheimer's Disease Points for Accelerated Epigenetic Aging in Neurodegeneration

Alzheimer's disease (AD) is characterized by specific alterations of brain DNA methylation (DNAm) patterns. Age and sex, two major risk factors for AD, are also known to largely affect the epigenetic profiles in brain, but their contribution to AD-associated DNAm changes has been poorly investi...

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Detalles Bibliográficos
Publicado en:Front Aging Neurosci
Main Authors: Pellegrini, Camilla, Pirazzini, Chiara, Sala, Claudia, Sambati, Luisa, Yusipov, Igor, Kalyakulina, Alena, Ravaioli, Francesco, Kwiatkowska, Katarzyna M., Durso, Danielle F., Ivanchenko, Mikhail, Monti, Daniela, Lodi, Raffaele, Franceschi, Claudio, Cortelli, Pietro, Garagnani, Paolo, Bacalini, Maria Giulia
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006465/
https://ncbi.nlm.nih.gov/pubmed/33790779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.639428
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