Alcohol Use Is Associated With Intestinal Dysbiosis and Dysfunctional CD8(+) T-Cell Phenotypes in Persons With Human Immunodeficiency Virus

BACKGROUND: Inflammation persists among persons with human immunodeficiency virus (PWH) despite effective antiretroviral therapy and may contribute to T-cell dysfunction. Alcohol use is prevalent among PWH and promotes intestinal leak, dysbiosis, and a proinflammatory milieu. Whether alcohol use is...

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Vydáno v:J Infect Dis
Hlavní autoři: Maffei, Vincent J, Siggins, Robert W, Luo, Meng, Brashear, Meghan M, Mercante, Donald E, Taylor, Christopher M, Molina, Patricia, Welsh, David A
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006423/
https://ncbi.nlm.nih.gov/pubmed/32725203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa461
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