The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway

Background: The incidence of colorectal cancer (CRC) has been increasing worldwide in recent years. Targeting cancer stem cells (CSCs) in CRC remains a difficult challenge. KDM2B and EZH2 play important role in the maintenance of CSCs' self-renewal capacity and tumorigenic ability; however, the...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Sanches, Jaceline Gisliane Pires, Song, Bo, Zhang, Qingqing, Cui, Xinye, Yabasin, Iddrisu Baba, Ntim, Michael, Li, Xinlong, He, Jiabei, Zhang, Yao, Mao, Jun, Lu, Ying, Li, Lianhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006351/
https://ncbi.nlm.nih.gov/pubmed/33791221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.637298
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