The m(6)A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m(6)A-Dependent Manner

OBJECTIVES: N(6)-methyladenosine (m(6)A) RNA methylation is implicated in the progression of multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in gastric cancer (GC), while the biological mechanisms via which YTHDF1 regulates gastric tumorigenesis through m(6)A modifi...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Chen, Xiao-Yu, Liang, Rui, Yi, You-Cai, Fan, Hui-Ning, Chen, Ming, Zhang, Jing, Zhu, Jin-Shui
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8006284/
https://ncbi.nlm.nih.gov/pubmed/33791305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.647702
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