Mesenchymal Stromal Cell Derived Membrane Particles Are Internalized by Macrophages and Endothelial Cells Through Receptor-Mediated Endocytosis and Phagocytosis

Mesenchymal stromal cells (MSC) are a promising therapy for inflammatory diseases. However, MSC are large and become trapped in the lungs after intravenous infusion, where they have a short survival time. To steer MSC immunoregulatory therapy beyond the lungs, we generated nm-sized particles from MS...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: da Costa Gonçalves, Fabiany, Korevaar, Sander S., Ortiz Virumbrales, Maitane, Baan, Carla C., Reinders, Marlies E. J., Merino, Ana, Lombardo, Eleuterio, Hoogduijn, Martin J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005704/
https://ncbi.nlm.nih.gov/pubmed/33790914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.651109
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