Pharmacologic Inhibition of ADAM10 Attenuates Brain Tissue Loss, Axonal Injury and Pro-inflammatory Gene Expression Following Traumatic Brain Injury in Mice

The α-secretase A disintegrin and metalloprotease 10 (ADAM10) regulates various physiological and pathophysiological processes. Despite its broad functional implications during development, plasticity, and disease, no pharmacological approaches to inhibit ADAM10 in acute brain injury have been repor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Cell Dev Biol
Egile Nagusiak: Appel, Dominik, Hummel, Regina, Weidemeier, Martin, Endres, Kristina, Gölz, Christina, Schäfer, Michael K. E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Cell and Developmental Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005610/
https://ncbi.nlm.nih.gov/pubmed/33791311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.661462
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