Analysis of HPV Integrations in Mexican Pre-Tumoral Cervical Lesions Reveal Centromere-Enriched Breakpoints and Abundant Unspecific HPV Regions

Human papillomavirus (HPV) DNA integration is a crucial event in cervical carcinogenesis. However, scarce studies have focused on studying HPV integration (HPVint) in early-stage cervical lesions. Using HPV capture followed by sequencing, we investigated HPVint in pre-tumor cervical lesions. Employi...

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Udgivet i:Int J Mol Sci
Main Authors: Garza-Rodríguez, María Lourdes, Oyervides-Muñoz, Mariel Araceli, Pérez-Maya, Antonio Alí, Sánchez-Domínguez, Celia Nohemí, Berlanga-Garza, Anais, Antonio-Macedo, Mauro, Valdés-Chapa, Lezmes Dionicio, Vidal-Torres, Diego, Vidal-Gutiérrez, Oscar, Pérez-Ibave, Diana Cristina, Treviño, Víctor
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005155/
https://ncbi.nlm.nih.gov/pubmed/33810183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063242
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