A Profound Basic Characterization of eIFs in Gliomas: Identifying eIF3I and 4H as Potential Novel Target Candidates in Glioma Therapy

SIMPLE SUMMARY: Gliomas are brain tumors with currently limited therapy options. Glioma growth and proliferation is regulated by the mTOR pathway together with eukaryotic initiation factors (eIFs). In this work we show a profound basic characterization of eIFs in human gliomas and demonstrate increa...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Krassnig, Stefanie, Wohlrab, Christina, Golob-Schwarzl, Nicole, Raicht, Andrea, Schatz, Christoph, Birkl-Toeglhofer, Anna Maria, Skofler, Christina, Gantenbein, Nadine, Leoni, Marlene, Asslaber, Martin, Leber, Stefan L., Mahdy-Ali, Kariem, von Campe, Gord, Mayer, Marlene, Borenich, Andrea, Weis, Serge, Benesch, Martin, Haybaeck, Johannes
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004965/
https://ncbi.nlm.nih.gov/pubmed/33807050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061482
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