Persistent Inflammatory Stimulation Drives the Conversion of MSCs to Inflammatory CAFs That Promote Pro-Metastatic Characteristics in Breast Cancer Cells

SIMPLE SUMMARY: Breast cancer progression is prominently regulated by the persistent presence of inflammatory mediators and by stromal cells that are located in the tumors. Here, we connected these two elements by demonstrating that potent pro-inflammatory cytokines (tumor necrosis factor α and inte...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Rubinstein-Achiasaf, Linor, Morein, Dina, Ben-Yaakov, Hagar, Liubomirski, Yulia, Meshel, Tsipi, Elbaz, Eti, Dorot, Orly, Pichinuk, Edward, Gershovits, Michael, Weil, Miguel, Ben-Baruch, Adit
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004890/
https://ncbi.nlm.nih.gov/pubmed/33806906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061472
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