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Transglycosylation Activity of Engineered Bifidobacterium Lacto-N-Biosidase Mutants at Donor Subsites for Lacto-N-Tetraose Synthesis

The health benefits of human milk oligosaccharides (HMOs) make them attractive targets as supplements for infant formula milks. However, HMO synthesis is still challenging and only two HMOs have been marketed. Engineering glycoside hydrolases into transglycosylases may provide biocatalytic routes to...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Castejón-Vilatersana, Mireia, Faijes, Magda, Planas, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004761/
https://ncbi.nlm.nih.gov/pubmed/33810098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063230
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