Growth cone repulsion to Netrin-1 depends on lipid raft microdomains enriched in UNC5 receptors

During brain development, Uncoordinated locomotion 5 (UNC5) receptors control axonal extension through their sensing of the guidance molecule Netrin-1. The correct positioning of receptors into cholesterol-enriched membrane raft microdomains is crucial for the efficient transduction of the recognize...

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Publicado en:Cell Mol Life Sci
Autores principales: Hernaiz-Llorens, Marc, Roselló-Busquets, Cristina, Durisic, Nela, Filip, Adam, Ulloa, Fausto, Martínez-Mármol, Ramón, Soriano, Eduardo
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8004515/
https://ncbi.nlm.nih.gov/pubmed/33095273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03663-z
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