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Iron-Bound Lipocalin-2 from Tumor-Associated Macrophages Drives Breast Cancer Progression Independent of Ferroportin

Macrophages supply iron to the breast tumor microenvironment by enforced secretion of lipocalin-2 (Lcn-2)-bound iron as well as the increased expression of the iron exporter ferroportin (FPN). We aimed at identifying the contribution of each pathway in supplying iron for the growing tumor, thereby f...

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Dettagli Bibliografici
Pubblicato in:Metabolites
Autori principali: Mertens, Christina, Schnetz, Matthias, Rehwald, Claudia, Grein, Stephan, Elwakeel, Eiman, Weigert, Andreas, Brüne, Bernhard, Jung, Michaela
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8003561/
https://ncbi.nlm.nih.gov/pubmed/33808732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo11030180
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