Epigenetic Treatment of Urothelial Carcinoma Cells Sensitizes to Cisplatin Chemotherapy and PARP Inhibitor Treatment

SIMPLE SUMMARY: Muscle-invasive urothelial carcinoma of the bladder (UC) is treated with chemotherapies based on the DNA-damaging drug cisplatin, which only works temporarily due to the development of drug resistance. In this study, we show that it may be possible to overcome such resistances by tre...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Thy, Sophia, Hommel, Alexandra, Meneceur, Sarah, Bartkowiak, Anna L., Schulz, Wolfgang A., Niegisch, Günter, Hoffmann, Michèle J.
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002916/
https://ncbi.nlm.nih.gov/pubmed/33803654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061376
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