Chromatin Regulator SRG3 Overexpression Protects against LPS/D-GalN-Induced Sepsis by Increasing IL10-Producing Macrophages and Decreasing IFNγ-Producing NK Cells in the Liver

We previously showed that ubiquitous overexpression of the chromatin remodeling factor SWItch3-related gene (SRG3) promotes M2 macrophage differentiation, resulting in anti-inflammatory responses in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Since hepatic macrophages...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Lee, Sung Won, Park, Hyun Jung, Jeon, Jungmin, Park, Yun Hoo, Kim, Tae-Cheol, Jeon, Sung Ho, Seong, Rho Hyun, Van Kaer, Luc, Hong, Seokmann
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002522/
https://ncbi.nlm.nih.gov/pubmed/33809795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22063043
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