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Synthesis of Piperidine Nucleosides as Conformationally Restricted Immucillin Mimics
The de novo synthesis of piperidine nucleosides from our homologating agent 5,6-dihydro-1,4-dithiin is herein reported. The structure and conformation of nucleosides were conceived to faithfully resemble the well-known nucleoside drugs Immucillins H and A in their bioactive conformation. NMR analysi...
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| Pubblicato in: | Molecules |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8001838/ https://ncbi.nlm.nih.gov/pubmed/33809603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26061652 |
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