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Did Amino Acid Side Chain Reactivity Dictate the Composition and Timing of Aminoacyl-tRNA Synthetase Evolution?

The twenty amino acids in the standard genetic code were fixed prior to the last universal common ancestor (LUCA). Factors that guided this selection included establishment of pathways for their metabolic synthesis and the concomitant fixation of substrate specificities in the emerging aminoacyl-tRN...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Hendrickson, Tamara L., Wood, Whitney N., Rathnayake, Udumbara M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001834/
https://ncbi.nlm.nih.gov/pubmed/33809136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12030409
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