Influence of UGT1A1 *6/*28 Polymorphisms on Irinotecan-Related Toxicity and Survival in Pediatric Patients with Relapsed/Refractory Solid Tumors Treated with the VIT Regimen

OBJECTIVE: The association between UGT1A1*6/*28 polymorphisms and treatment outcomes of irinotecan in children remains unknown. This retrospective study investigated the influence of UGT1A1*6/*28 polymorphisms on irinotecan toxicity and survival of pediatric patients with relapsed/refractory solid t...

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Detalles Bibliográficos
Publicado en:Pharmgenomics Pers Med
Main Authors: Zhu, Xiaoqin, Zhu, Jia, Sun, Feifei, Zhen, Zijun, Zhou, Dalei, Lu, Suying, Huang, Junting, Que, Yi, Zhang, Lian, Cai, Ruiqing, Wang, Juan, Zhang, Yizhuo
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2021
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001723/
https://ncbi.nlm.nih.gov/pubmed/33790625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S292556
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