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Regulation of K(+) Conductance by a Hydrogen Bond in Kv2.1, Kv2.2, and Kv1.2 Channels

The slow inactivation of voltage-gated potassium (Kv) channels plays an important role in controlling cellular excitability. Recently, the two hydrogen bonds (H-bonds) formed by W434-D447 and T439-Y445 have been reported to control the slow inactivation in Shaker potassium channels. The four residue...

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Vydáno v:Membranes (Basel)
Hlavní autoři: Zhang, Yuchen, Zhang, Xuefeng, Liu, Cuiyun, Hu, Changlong
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001480/
https://ncbi.nlm.nih.gov/pubmed/33803465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes11030190
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