Metal-Bound Methisazone; Novel Drugs Targeting Prophylaxis and Treatment of SARS-CoV-2, a Molecular Docking Study

SARS-CoV-2 currently lacks effective first-line drug treatment. We present promising data from in silico docking studies of new Methisazone compounds (modified with calcium, Ca; iron, Fe; magnesium, Mg; manganese, Mn; or zinc, Zn) designed to bind more strongly to key proteins involved in replicatio...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Abdelaal Ahmed Mahmoud M. Alkhatip, Ahmed, Georgakis, Michail, Montero Valenzuela, Lucio R., Hamza, Mohamed, Farag, Ehab, Hodgkinson, Jaqui, Hosny, Hisham, Kamal, Ahmed M., Wagih, Mohamed, Naguib, Amr, Yassin, Hany, Algameel, Haytham, Elayashy, Mohamed, Abdelhaq, Mohamed, Younis, Mohamed I., Mohamed, Hassan, Abdulshafi, Mohammed, Elramely, Mohamed A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8001373/
https://ncbi.nlm.nih.gov/pubmed/33804129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062977
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