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Probing the Structure and Function of the Cytosolic Domain of the Human Zinc Transporter ZnT8 with Nickel(II) Ions

The human zinc transporter ZnT8 provides the granules of pancreatic β-cells with zinc (II) ions for assembly of insulin hexamers for storage. Until recently, the structure and function of human ZnTs have been modelled on the basis of the 3D structures of bacterial zinc exporters, which form homodime...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Catapano, Maria Carmen, Parsons, Douglas S., Kotuniak, Radosław, Mladěnka, Přemysl, Bal, Wojciech, Maret, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000985/
https://ncbi.nlm.nih.gov/pubmed/33799326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062940
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