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LINflow: a computational pipeline that combines an alignment-free with an alignment-based method to accelerate generation of similarity matrices for prokaryotic genomes

BACKGROUND: Computing genomic similarity between strains is a prerequisite for genome-based prokaryotic classification and identification. Genomic similarity was first computed as Average Nucleotide Identity (ANI) values based on the alignment of genomic fragments. Since this is computationally expe...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Tian, Long, Mazloom, Reza, Heath, Lenwood S., Vinatzer, Boris A.
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8000461/
https://ncbi.nlm.nih.gov/pubmed/33828908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10906
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