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NTRK Fusions in Sarcomas: Diagnostic Challenges and Clinical Aspects
Tropomyosin receptor kinase (TK) is encoded by the neurotrophic tyrosine receptor kinase genes (NTRK) 1, 2, and 3, whose activation plays an important role in cell cycle proliferation and survival. Fusions of one of these genes can lead to constitutive activation of TRK, which can potentially be onc...
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| Publicado no: | Diagnostics (Basel) |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8000177/ https://ncbi.nlm.nih.gov/pubmed/33803146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/diagnostics11030478 |
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