Vagus nerve stimulation activates two distinct neuroimmune circuits converging in the spleen to protect mice from kidney injury

Acute kidney injury is highly prevalent and associated with high morbidity and mortality, and there are no approved drugs for its prevention and treatment. Vagus nerve stimulation (VNS) alleviates inflammatory diseases including kidney disease; however, neural circuits involved in VNS-induced tissue...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tanaka, Shinji, Abe, Chikara, Abbott, Stephen B. G., Zheng, Shuqiu, Yamaoka, Yusuke, Lipsey, Jonathan E., Skrypnyk, Nataliya I., Yao, Junlan, Inoue, Tsuyoshi, Nash, William T., Stornetta, Daniel S., Rosin, Diane L., Stornetta, Ruth L., Guyenet, Patrice G., Okusa, Mark D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999957/
https://ncbi.nlm.nih.gov/pubmed/33737395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2021758118
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