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LipoParticles: Lipid-Coated PLA Nanoparticles Enhanced In Vitro mRNA Transfection Compared to Liposomes

The approval of two mRNA vaccines as urgent prophylactic treatments against Covid-19 made them a realistic alternative to conventional vaccination methods. However, naked mRNA is rapidly degraded by the body and cannot effectively penetrate cells. Vectors capable of addressing these issues while all...

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Publicat a:Pharmaceutics
Autors principals: Ayad, Camille, Libeau, Pierre, Lacroix-Gimon, Céline, Ladavière, Catherine, Verrier, Bernard
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999670/
https://ncbi.nlm.nih.gov/pubmed/33809164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13030377
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