Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes

SIMPLE SUMMARY: Colorectal cancer (CRC) is one of the leading causes of cancer mortality; it typically originates as adenomas that progress over time to carcinomas. We decided to investigate the accumulation of numerous genomic alterations during tumour progression by using a mouse model with three...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Dionellis, Vasilis S., Norkin, Maxim, Karamichali, Angeliki, Rossetti, Giacomo G., Huelsken, Joerg, Ordonez-Moran, Paloma, Halazonetis, Thanos D.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999300/
https://ncbi.nlm.nih.gov/pubmed/33809306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13061267
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