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Danegaptide Prevents TGFβ1-Induced Damage in Human Proximal Tubule Epithelial Cells of the Kidney

Chronic kidney disease (CKD) is a global health problem associated with a number of comorbidities. Recent evidence implicates increased hemichannel-mediated release of adenosine triphosphate (ATP) in the progression of tubulointerstitial fibrosis, the main underlying pathology of CKD. Here, we evalu...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Squires, Paul E., Price, Gareth W., Mouritzen, Ulrik, Potter, Joe A., Williams, Bethany M., Hills, Claire E.
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999212/
https://ncbi.nlm.nih.gov/pubmed/33802083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22062809
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