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Caprine MAVS Is a RIG-I Interacting Type I Interferon Inducer Downregulated by Peste des Petits Ruminants Virus Infection

The mitochondrial antiviral-signaling protein (MAVS, also known as VISA, IPS-1, or CARDIF) plays an essential role in the type I interferon (IFN) response and in retinoic acid-inducible gene I (RIG-I) mediated antiviral innate immunity in mammals. In this study, the caprine MAVS gene (caMAVS, 1566 b...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Miao, Qiuhong, Qi, Ruibing, Meng, Chunchun, Zhu, Jie, Tang, Aoxing, Dong, Dandan, Guo, Hongyuan, van Oers, Monique M., Pijlman, Gorben P., Liu, Guangqing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7998690/
https://ncbi.nlm.nih.gov/pubmed/33807534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13030409
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